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On the Record · Opko Health

Opko Health acquisitions, on the record

The businesses Opko Health bought and sold, as its annual reports describe them, with the cash it reported paying for acquisitions each year and every deal filing since 2016.

Deals its annual reports describe

BusinessDealWhenValue
ModeX Therapeutics, Inc.
Word for word“On May 9, 2022, the Company entered into the ModeX Merger Agreement (as defined in Note 1 to the audited consolidated financial statements contained in this Annual Report on Form 10-K), pursuant to which we acquired ModeX.” 10-K for 2023
agreed acquisitionMay 9, 2022—
GeneDx LLC (f/k/a GeneDx, Inc.)
Word for word“Pursuant to the GeneDx Merger Agreement, on April 29, 2022, GeneDx Holdings Corp. (formerly, Sema4), acquired GeneDx from us for an upfront payment of $150 million in cash, together with 80.0 million shares of GeneDx Holdings Common Stock, subject to a customary purchase price adjustment mechanism.” 10-K for 2023
agreed divestitureOn April 29, 2022an upfront payment of $150 million in cash, together with 80.0 million shares of GeneDx Holdings Common Stock, subject to a customary purchase price adjustment mechanism
Transition Therapeutics
Word for word“In 2016, we acquired Transition Therapeutics, which was developing multiple drug candidates that included OPK88003 (a long acting oxyntomodulin) and OPK88004 (SARM), each of which is licensed from Eli Lilly and has patents granted worldwide covering the compounds and their use in their respective indications.” 10-K for 2023
acquisition2016—
EirGen
Word for word“During 2015, we acquired EirGen, a specialty pharmaceutical company based in Ireland.” 10-K for 2023
acquisitionDuring 2015—
select assets of BioReference
Word for word“The BioReference Transaction closed on September 16, 2024, and upon closing, Labcorp paid to the Company aggregate consideration of $237.5 million in cash, subject to certain adjustments as set forth in the Labcorp Asset Purchase Agreement.” 10-K for 2024
agreed divestitureThe BioReference Transaction closed on September 16, 2024$237.5 million in cash
GeneDx LLC
Word for word“We originally acquired shares of GeneDx Holdings in the 2022 disposition of our former subsidiary, GeneDx LLC (“GeneDx”) and subsequently acquired additional shares in an underwritten offering by GeneDx Holdings.” 10-K for 2024
divestiture2022—
BioReference's laboratory testing businesses focused on clinical diagnostics, reproductive health, and women's health across the United States, excluding New York and New Jersey
Word for word“• September 2024 BioReference Transaction: We completed the sale of laboratory testing businesses focused on clinical diagnostics, reproductive health, and women's health across the United States, excluding New York and New Jersey, for $237.5 million in cash.” 10-K for 2025
divestitureSeptember 2024$237.5 million
ModeX
Word for word“In May 2022, we acquired ModeX, a biotech company developing multi-specific immune therapies focused on oncology, immunology and infectious diseases.” 10-K for 2025
acquisitionMay 2022—
As filedReported in the company's financial data (XBRL), each linked to its filing
Fiscal year endedCash paid for acquisitions (net of cash acquired)Cash received from selling businesses
2016-12-31−$15.9 million—
2017-12-31$0—
2018-12-31$0—
2019-12-31$0—
2020-12-31$0—
2021-12-31$4 million—
2022-12-31$1.8 million$0
2023-12-31$0$0
2024-12-31$0$210.4 million
2025-12-31—$197.8 million

Deal filings since 2016

Read from Opko Health’s annual reports (10-K for 2025, 10-K for 2024, 10-K for 2023) and the financial data it files with the SEC, as of 2026-02-26. Every quotation is word for word from the filing linked beside it; how these pages are built and checked. The full record is in its company data sheet.